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| DOE optimization of the analytical method. These include:
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| Sensitivity;
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| Upper and Lower limits of quantification (ULOQ and LLOQ);
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| The precision profile calculation, reported as the estimated %CV at each non-zero calibrator level; and
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| Accuracy, as measured by the estimated concentration from the mean response for each control sample, divided by the target concentration for that control sample.
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| Run ID
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| Date
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| Analysis Summary Current DOE Values
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| Run ID
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| transform
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| s-pooled
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| df for s-pooled
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| Bartletts p
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| CV@ (at the extremes of the curve)
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| Sensitivity
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| Analysis Summary Current DOE Values
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| Parameter Value 95% Lo Lim 95% Hi Lim
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| RunID example1
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| transform y'=(y)^1.5
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| s-pooled 44.248814
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| s-pooled df 46.0
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| Bartlett's p 0.427885
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| Box-Cox Slope 0.578956
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| Box-Cox R squared 0.049409
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| LLOQ@15% 0.645 0.49 0.985
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| ULOQ@15% 5.0 3.66 5.0
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| Sensitivity 0.215589 0.177516 0.274703
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| CV@1.0 11.85% 9.85% 14.88%
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| X-Calc@1.0 1.089492 0.968259 1.219807
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| C/T@1.0 108.95% 96.83% 121.98%
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